A Unified Forensics Analysis Approach to Digital Investigation

Digital forensics is now essential in addressing cybercrime and cyber-enabled crime but potentially it can have a role in almost every other type of crime. Given technology's continuous development and prevalence, the widespread adoption of technologies among society and the subsequent digital footprints that exist, the analysis of these technologies can help support investigations. The abundance of interconnected technologies and telecommunication platforms has significantly changed the nature of digital evidence. Subsequently, the nature and characteristics of digital forensic cases involve an enormous volume of data heterogeneity, scattered across multiple evidence sources, technologies, applications, and services. It is indisputable that the outspread and connections between existing technologies have raised the need to integrate, harmonise, unify and correlate evidence across data sources in an automated fashion. Unfortunately, the current state of the art in digital forensics leads to siloed approaches focussed upon specific technologies or support of a particular part of digital investigation. Due to this shortcoming, the digital investigator examines each data source independently, trawls through interconnected data across various sources, and often has to conduct data correlation manually, thus restricting the digital investigator’s ability to answer high-level questions in a timely manner with a low cognitive load. Therefore, this research paper investigates the limitations of the current state of the art in the digital forensics discipline and categorises common investigation crimes with the necessary corresponding digital analyses to define the characteristics of the next-generation approach. Based on these observations, it discusses the future capabilities of the next-generation unified forensics analysis tool (U-FAT), with a workflow example that illustrates data unification, correlation and visualisation processes within the proposed method.</jats:p

Medical Residents of Family Medicine Management of Depression, Anxiety and Burnout Syndrome in KSA

This study aimed at analyzing the Medical Residents of family medicine management of depression, anxiety and burnout syndrome in Kingdom Saudi Arabia. This study also describes the relationship between wellness behaviors and measures of well-being at the start of family medicine residency in Kingdom Saudi Arabia. The researcher adopted the Methodology of descriptive statistics. And the study concluded that the innovative curriculum and activities that focus on wellness behaviors and healthy lifestyle choices for physicians in training are needed. The ACGME mandate on implementation of duty hours for residents may show a positive effect in future generations of physicians. Family medicine programs can lead in creating additional institutional methodologies to support a culture of wellness for residents, faculty, and staff, thus promoting a lifelong commitment to self-care and an emphasis on prevention and health promotion for our patients.

Patients with Chronic Kidney Disease and Their Quality of Life

This study aimed at exploring the assessment of Quality of Life (QOL) in patients with Chronic Kidney Disease (CKD), and aiming at assessing the QOL of patients with stages 1–5 Chronic Kidney Disease CKD on conservative treatment in order to identify a possible association between Quality Of Life QOL and progression of kidney insufficiency. The results were compared with those obtained for patients on hemodialysis. Sociodemographic, clinical and laboratory data were also evaluated. And the study concluded that research efforts have expanded significantly to determine the state of pediatric CKD patient HRQOL and the factors that impact HRQOL across all stages of CKD and all modalities of renal replacement therapy. Data from all studies suggest that children with a renal transplant fare better with respect to HRQOL than those receiving dialysis.

Correlation between the clinical severity of laryngomalacia and endoscopic findings

Objective: To correlate the clinical severity of laryngomalacia (LM) with endoscopic findings, swallowing evaluations and polysomnography in a cohort of patients. Method: We conducted a retrospective analysis between 2017-2018 on a cohort of patients diagnosed with upper airway obstruction (UAO), stridor, noisy breathing or laryngomalacia. This study took place at the Pediatric Pulmonology Department, Riley Children's Hospital, Indianapolis, United States of America. Results: There were 157 patients with laryngomalacia included in the study. Patients with severe LM were significantly younger than those with mild LM (p=0.0214) and moderate LM (p=0.0220). Subjects with type I of LM were significantly older than type III (p=0.0051). When associations were tested between polysomnogram (PSG) variables and clinical severity, there were significant associations with age at PSG. The overall apnea-hypopnea index (AHI) in mild (p=0.0103) and moderate (p=0.0242) were significantly lower than the severe group. The rapid eye movement (REM) AHI was significantly lower in moderate cases than severe (p=0.0134). The end-tidal carbon dioxide (EtCO2) peak was significantly lower in mild cases than severe (p=0.0141). The total sleep time (TST) peripheral capillary oxygen saturation (SpO2) 90% occurs in both mild (p=0.0197) and moderate (p=0.0498) were significantly lower than the severe group. Conclusions: The severity of the clinical manifestations of LM did not correlate with the different endoscopic types in our study. The presence of cyanosis was associated with type III LM. Rapid eye movement AHI and EtCO2 in polysomnogram were remained significantly associated with clinical severity

Asymptomatic Incisional Endometrioma Presenting as Abdominal Wall Mass: A case report

Asymptomatic incisional endometrioma of the anterior abdominal wall is rare. Clinical diagnosis may be difficult. We present a 26 year old woman with incisional abdominal wall endometrioma discovered 5 years after caeserian section. It was painless and there was no change in size with menstruation. The patient's body size was average with a palpable lump at the edge of the caeserian section scar. Clinically desmoid tumour was suspected. The patient underwent surgical excision. Histopathology confirmed endometrioma. There was no recurrence on three months follow-up. Keywords: endometriosis, endometrioma, abdominal wall, asymptomatic, caeserian sca

A New Variant Mutation in SKIV2L Gene in Case of Trichohepatoenteric Syndrome

Trichohepatoenteric syndrome is an autosomal recessive genetic disease with an estimated prevalence of 1:100,000. The mutation of the disease is placed either in SKIV2L or TTC37 genes. The onset of presentation is variable, but symptoms usually start with intractable diarrhea associated with woolly hair abnormality, immune dysfunction, and sometimes hepatic abnormality. This case is of a 10-month-old girl who was born at 37 + 2 weeks due to symmetrical intrauterine growth restriction (IUGR), with a low birth weight (1320 g). It was noticed during her stay in NICU that she had excessive diarrhea on day 8. Gastroenterology suggested starting an extensively-hydrolyzed formula, but no improvement noticed. The multidisciplinary teams decided to order whole-exome sequencing analysis after excluding diarrhea causes. The analysis detected a new variant mutation (c.1297C &gt; T) p. (Arg433Cys). To our knowledge, this is the first time detected in a homozygous state in the SKIV2L gene, as this variant mutation has not been described in any previous literature. Our case was managed mainly by total parenteral nutrition. The patient responded to the treatment appropriately

Table1_Factors influencing the mental health of caregivers of children with cerebral palsy.docx

ObjectivesCaregivers of children with cerebral palsy have a huge burden which might affect their mental health. This study aimed to determine the different factors affecting the mental health of caregivers of children with cerebral palsy and to raise awareness among healthcare providers.MethodsA cross-sectional study was conducted among caregivers of children with cerebral palsy in National Guard Health Affairs-Jeddah, Saudi Arabia, using the Depression Anxiety Stress Scale-21, which is a validated questionnaire that assesses: depression, anxiety, and stress. This questionnaire was used to assess the mental health of the caregivers. In addition, factors that reflected the child's health condition, such as visual impairment, number of emergency department visits, and number of Pediatric Intensive Care Unit admissions were also reported to investigate the impact on the caregiver's mental health.ResultsThe study sample consisted of 40 caregivers, of which 72.5% were mothers. According to the Depression Anxiety Stress Scale-21 score, 12.5% (n = 5) of the caregivers had moderate depression scores, 10% (n = 4) revealed extremely severe depression, and 10% (n = 4) showed moderate anxiety. Furthermore, 12.5% (n = 5), 15% (n = 6), and 7.5% (n = 3) of the caregivers have scored as moderate, severe, and extremely severe stress levels, respectively. Caregivers’ depression, anxiety, and stress scores were significantly (p ≤ 0.05) associated with the impact of vision of their dependent children, frequent hospital admissions, and frequent emergency department visits. Increased Pediatric Intensive Care Unit admissions in the past year were also significantly associated with higher caregiver anxiety scores.ConclusionTo the best of our knowledge, the dimension of caregivers’ stress and anxiety and their association with the children's dependency level is not well documented in our region. Caregivers of children with cerebral palsy reported having mental health challenges associated with the children's visual impairment, frequent need for acute medical care, and hospital admissions. Healthcare workers should provide early and proactive planning of medical and social support for children with cerebral palsy and their families using a family-centered approach.</p